Systemic immune-inflammatory index predicts fragility fracture risk in postmenopausal anemic females with type 2 diabetes mellitus: evidence from a longitudinal cohort study

Table 2 Pearson and partial correlation analyses for the relationship between the SII and BMD and the next 10-year probability of MOF and HF calculated by the FRAX in postmenopausal women with T2DM

	LS BMD		FN BMD		TH BMD		MOF		HF
	r	p	r	p	r	p	r	p	r	p
Model I	−0.037	0.454	−0.133	0.006^*	−0.136	0.005^*	0.128	0.008^*	0.144	0.003^*
Model II	−0.066	0.175	−0.101	0.039^*	−0.127	0.009^*	0.093	0.056	0.100	0.041^*
Model III	−0.027	0.577	−0.037	0.451	−0.052	0.283	0.036	0.462	0.041	0.404

Model I: adjusted for none. Model II: adjusted for age and hypertension. Model III: adjusted for age, hypertension, FT4, 25(OH) D, Hb, ALB, and Cr
Abbreviations: SII systemic immune-inflammatory index, BMD bone mineral density, MOF major osteoporotic fracture, HF hip fracture, FRAX fracture risk assessment tool, T2DM type 2 diabetes mellitus, LS lumbar spine, FN femoral neck, TH total hip, FT4 free thyroxine, 25-(OH) D 25-hydroxy vitamin D, Hb hemoglobin, ALB serum albumin, Cr creatinine
^*P < 0.05

ISSN: 1472-6823